(Trp63, Trp64) -C3a (63-77)
(Trp63, Trp64) -C3a (63-77) is a C3a synthetic analogue peptide, which exhibits Ca2+ stimulating efficacy in human neutrophils and hC3aR or mC3aR expressing RBL-2H3 cells with EC50 of 9.5, 2.0 and 0.8 nM, respectively[1].
Product Specifications
CAS Number
[130154-64-2]
UNSPSC
12352209
Target
Complement System
Type
Peptides
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/trp63-trp64-c3a-63-77.html
Purity
99.23
Solubility
DMSO : 2 mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@H](C(NCC(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CC=C(C=C3)O)=O)=O)=O)=O)CC4=CNC5=CC=CC=C45)=O
Molecular Formula
C86H134N26O18
Molecular Weight
1820.15
References & Citations
[1]Ames RS, et al., Evidence that the receptor for C4a is distinct from the C3a receptor. Immunopharmacology. 1997 Dec;38 (1-2) :87-92.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
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