T-22
T-22 (polyphemusin II with [Tyr5,12, Lys7]) is a new synthetic peptide that fights HIV, with an EC50 of 0.008 μg/mL and a CC50 of 54 μg/mL. T22 promotes plant height, photosynthesis, total chlorophyll content, and gas exchange in tomatoes, and it can resist CMV[1][2].
Product Specifications
CAS Number
147658-54-6
Product Name Alternative
[Tyr5,12, Lys7]-Polyphemusin II
UNSPSC
12352209
Target
CMV; HIV
Type
Peptides
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/t-22.html
Smiles
C([C@@H](C(N[C@@H]1C(=O)N[C@@H](CC2=CC=C(O)C=C2)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@]3(C(=O)N[C@@H](CC4=CC=C(O)C=C4)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CC5=CC=C(O)C=C5)C(=O)N[C@@](CSSC3)(C(=O)N[C@@H](CC6=CC=C(O)C=C6)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@H](C(N[C@@H](CCCNC(=N)N)C(N)=O)=O)CSSC1)[H])[H])=O)NC([C@@H](NC([C@H](CCCNC(=N)N)N)=O)CCCNC(=N)N)=O)C=7C=8C(NC7)=CC=CC8
Molecular Formula
C109H164N38O22S4
Molecular Weight
2486.97
References & Citations
[1]Masao Masuda, et al. A novel anti-HIV synthetic peptide, T-22 ([Tyr5,12, Lys7]-polyphemusin II) . Biochemical and Biophysical Research Communications. Volume 189, Issue 2, 15 December 1992, Pages 845-850.|[2]Antonella Vitti, et al. Trichoderma harzianum T-22 Induces Systemic Resistance in Tomato Infected by Cucumber mosaic virus. Front Plant Sci. 2016 Oct 10:7:1520.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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