Cynomolgus Mesothelin / MSLN (296-580) Protein, His Tag (MALS verified)
Cynomolgus Mesothelin (296-580), His Tag (MSN-C52H6) is expressed from human 293 cells (HEK293) . It contains AA Asp 296 - Gly 580 (Accession # A0A2K5TW94-1) .
Product Specifications
Background
Mesothelin (MSLN) is also known as CAK1 antigen, Pre-pro-megakaryocyte-potentiating factor, which belongs to the mesothelin family. Mesothelin / MSLN can be proteolytically cleaved into the following two chains by a furin-like convertase: Megakaryocyte-potentiating factor (MPF) and the cleaved form of mesothelin. Both MPF and the cleaved form of mesothelin are N-glycosylated. Mesothelin / MSLN can interacts with MUC16. The membrane-anchored forms of MSLN may play a role in cellular adhesion. MPF potentiates megakaryocyte colony formation in vitro.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 33.7 kDa. The protein migrates as 35-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
A0A2K5TW94-1
Expression Region
Asp 296 - Gly 580
Host
HEK293
Target
Mesothelin
Conjugation
Unconjugated
Tag
C-10xHis
Source
Cynomolgus
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Cynomolgus Mesothelin (296-580), His Tag (Cat. No. MSN-C52H6) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Human MSLN Antibody, Human IgG1 with a linear range of 0.06-2 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
33.7 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/MSN-C52H6.pdf
Species
Cynomolgus
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