Panobinostat-d4 (hydrochloride)
Panobinostat-d4 (hydrochloride) is deuterium labeled Panobinostat. Panobinostat (LBH589; NVP-LBH589) is a potent and orally active non-selective HDAC inhibitor, and has antineoplastic activities[1][2]. Panobinostat induces HIV-1 virus production even at low concentration range 8-31 nM, stimulates HIV-1 expression in latently infected cells[4]. Panobinostat induces cell apoptosis and autophagy. Panobinostat can be used for the study of refractory or relapsed multiple myeloma[3].
Product Specifications
Product Name Alternative
LBH589-d4 (hydrochloride) ; NVP-LBH589-d4 (hydrochloride)
UNSPSC
12352005
Target
Apoptosis; Autophagy; HDAC; HIV; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Apoptosis; Autophagy; Cell Cycle/DNA Damage; Epigenetics; Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Solubility
10 mM in DMSO
Smiles
ONC(/C=C/C(C([2H])=C1[2H])=C([2H])C([2H])=C1CNCCC2=C(C)NC3=CC=CC=C23)=O.Cl
Molecular Formula
C21H20D4ClN3O2
Molecular Weight
389.91
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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