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Salviandulin E

Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL[1][2].

Product Specifications

CAS Number

158994-32-2

UNSPSC

12352005

Target

Parasite

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/salviandulin-e.html

Solubility

10 mM in DMSO

Smiles

CC1=C2[C@@]3(C=CC4=C1[C@H](C5=COC=C5)OC4=O)C(C(OC3)=O)=C[C@@H](C2)O

Molecular Formula

C20H16O6

Molecular Weight

352.34

References & Citations

[1]Narukawa Y, et al. A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV. J Nat Med. 2006 Jul;60 (3) :206-209. |[2]Aoyagi Y, et al. Semisynthesis of salviandulin E analogues and their antitrypanosomal activity. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :442-6.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Isoform

Trypanosoma

Available Sizes

Frequently Asked Questions

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