Salviandulin E
Salviandulin E is a diterpenoid compound that can be isolated from Salvia leucantha CAV.. Salviandulin E shows antitrypanosomal activity against T. b. brucei GUTat 3.1 parasites with an IC50 value of 0.72 µg/mL[1][2].
Product Specifications
CAS Number
158994-32-2
UNSPSC
12352005
Target
Parasite
Type
Natural Products
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/salviandulin-e.html
Solubility
10 mM in DMSO
Smiles
CC1=C2[C@@]3(C=CC4=C1[C@H](C5=COC=C5)OC4=O)C(C(OC3)=O)=C[C@@H](C2)O
Molecular Formula
C20H16O6
Molecular Weight
352.34
References & Citations
[1]Narukawa Y, et al. A novel diterpenoid with a rearranged neoclerodane skeleton from Salvia leucantha CAV. J Nat Med. 2006 Jul;60 (3) :206-209. |[2]Aoyagi Y, et al. Semisynthesis of salviandulin E analogues and their antitrypanosomal activity. Bioorg Med Chem Lett. 2014 Jan 15;24 (2) :442-6.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Trypanosoma
Available Sizes
Frequently Asked Questions
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