Human Cathepsin D Protein, His Tag (active enzyme, MALS verified)
Human Cathepsin D Protein, His Tag (CAD-H52H3) is expressed from human 293 cells (HEK293) . It contains AA Leu 21 - Leu 412 (Accession # P07339-1) .
Product Specifications
Background
This gene encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin-like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in neuronal ceroid lipofuscinosis-10 and may be involved in the pathogenesis of several other diseases, including breast cancer and possibly Alzheimer's disease. [provided by RefSeq, Nov 2015]
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 44.5 kDa. The protein migrates as 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P07339-1
Expression Region
Leu 21 - Leu 412
Host
HEK293
Target
Cathepsin D
Conjugation
Unconjugated
Tag
C-10xHis
Source
Human
Stability
● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.
Endotoxin
1.0 EU per μg
Purity
95%
Format
Liquid
Buffer
12.5 mM MES, 75 mM NaCl, pH6.5
Additives
Glycerol
Molecular Weight
44.5 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Package Size
1mg*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CAD-H52H3.pdf
Species
Human
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