Benzothiazole

Benzothiazole is a natural occurring heterocyclic nuclei. Benzothiazole nucleus possesses a number of biological activities such as anticancer, antimicrobial, antidiabetic, anti-inflammatory, antileishmanial, and antiviral. Furthermore, Benzothiazole nucleus can function as an efficacious β-amyloid imaging agent[1][2][3][4].

Product Specifications

CAS Number

[95-16-9]

UNSPSC

12352005

Hazard Statement

H301+H311, H319, H332, H402

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Infection; Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/benzothiazole.html

Purity

99.04

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

C12=CC=CC=C1SC=N2

Molecular Formula

C7H5NS

Molecular Weight

135.19

Precautions

H301+H311, H319, H332, H402

References & Citations

[1]Ruhi Ali, et al. Biological Aspects of Emerging Benzothiazoles: A Short Review, Journal of Chemistry, vol. 2013, Article ID 345198, 12 pages, 2013.|[2]Côté C, et al. Immunotoxicity of Benzothiazole on Mytilus Edulis Following In Vitro Exposure of Hemocytes. J Xenobiot. 2016 Feb 10;5 (2) :5771.|[3]Singh M, et al. Benzothiazole derivatives bearing amide moiety: potential cytotoxic and apoptosis-inducing agents against cervical cancer. Anticancer Drugs. 2016;27 (6) :519-532.|[4]Ono M, et al. Push-pull benzothiazole derivatives as probes for detecting beta-amyloid plaques in Alzheimer's brains. Bioorg Med Chem. 2009;17 (19) :7002-7007.