Pamoic acid (Standard)
Pamoic acid (Standard) is the analytical standard of Pamoic acid. This product is intended for research and analytical applications. Pamoic acid (Embonic acid) is a potent GPR35 agonist with an EC50 of 79 nM. Pamoic acid exhibits neuroprotective and anti-inflammatory properties[1][2].
Product Specifications
CAS Number
130-85-8
Product Name Alternative
Embonic acid (Standard)
UNSPSC
12352005
Target
ERK; GPR35 ; Reference Standards
Type
Reference Standards
Related Pathways
GPCR/G Protein; MAPK/ERK Pathway; Others; Stem Cell/Wnt
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/pamoic-acid-standard.html
Smiles
OC1=C(C(O)=O)C=C2C(C=CC=C2)=C1CC3=C(O)C(C(O)=O)=CC4=C3C=CC=C4
Molecular Formula
C23H16O6
Molecular Weight
388.38
References & Citations
[1]Ozayra Sharmin, et al. Activation of GPR35 protects against cerebral ischemia by recruiting monocyte-derived macrophages. Sci Rep. 2020 Jun 10;10 (1) :9400. |[2]Pingwei Zhao, et al. Targeting of the orphan receptor GPR35 by pamoic acid: a potent activator of extracellular signal-regulated kinase and β-arrestin2 with antinociceptive activity. Mol Pharmacol. 2010 Oct;78 (4) :560-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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