Itopride (hydrochloride)
Itopride (HSR803) hydrochloride is a potent dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride hydrochloride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD) [1][2].
Product Specifications
CAS Number
122892-31-3
Product Name Alternative
HSR803
UNSPSC
12352005
Hazard Statement
H400, H410
Target
Bacterial; Cholinesterase (ChE) ; Dopamine Receptor
Type
Reference compound
Related Pathways
Anti-infection; GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/itopride-hydrochloride.html
Concentration
10mM
Purity
99.84
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(NCC1=CC=C(OCCN(C)C)C=C1)C2=CC=C(OC)C(OC)=C2.Cl
Molecular Formula
C20H27ClN2O4
Molecular Weight
394.89
Precautions
H400, H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
AChE; D2 Receptor
Available Sizes
Frequently Asked Questions
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