Thermopsidine
Thermopsidine (CC4) is a selective partial agonist at α4β2/α6β2 nAChR with EC50 values of 2.2 μM target α4β2[1].
Product Specifications
CAS Number
492-02-4
Product Name Alternative
CC4
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
NAChR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/thermopsidine.html
Smiles
[H][C@@]12CN3C([C@@](C2)([H])CN(C1)CCN4C[C@](C5)([H])C(N6C[C@]5([H])C4)=CC=CC6=O)=CC=CC3=O
Molecular Formula
C24H30N4O2
Molecular Weight
406.52
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Mariaelvina Sala, et al. CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 nAChR with improved selectivity for tobacco smoking cessation. Br J Pharmacol. 2013 Feb;168 (4) :835-49.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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