Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Apremilast (Standard)

Apremilast (Standard) is the analytical standard of Apremilast. This product is intended for research and analytical applications. Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1].

Product Specifications

CAS Number

608141-41-9

Product Name Alternative

CC-10004 (Standard)

UNSPSC

12352005

Target

Apoptosis; Phosphodiesterase (PDE) ; Reference Standards; TNF Receptor

Type

Reference Standards

Related Pathways

Apoptosis; Metabolic Enzyme/Protease; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/apremilast-standard.html

Smiles

CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OCC)=C3)CS(=O)(C)=O)=O)=C1C2=O)=O

Molecular Formula

C22H24N2O7S

Molecular Weight

460.50

References & Citations

[1]Perez-Aso M, et al. Apremilast, a novel phosphodiesterase 4 (PDE4) inhibitor, regulates inflammation through multiple cAMP downstream effectors. Arthritis Res Ther. 2015 Sep 15;17:249.|[2]Chen LG, et al. Determination of Apremilast in Rat Plasma by UPLC-MS-MS and Its Application to a Pharmacokinetic Study. J Chromatogr Sci. 2016 Sep;54 (8) :1336-40.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Tau (S198) Antibody
KC-12443-01 50 μL

Tau (S198) Antibody

Sign In for Pricing
View Details
Tau (S198) Antibody
KC-12443-02 100 µL

Tau (S198) Antibody

Sign In for Pricing
View Details
Tau (S198) Antibody
KC-12443-03 1 mL

Tau (S198) Antibody

Sign In for Pricing
View Details
APEX2 Human Gene Knockout Kit (CRISPR)
KN400320 1 Kit

APEX2 Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details
SEMA5B (NM_001031702) Human Over-expression Lysate
LY422156 100 µg

SEMA5B (NM_001031702) Human Over-expression Lysate

Sign In for Pricing
View Details
MAP126 (SPAG5) Human Gene Knockout Kit (CRISPR)
KN201783RB 1 Kit

MAP126 (SPAG5) Human Gene Knockout Kit (CRISPR)

Sign In for Pricing
View Details