WXM-1-170

WXM-1-170 (compound 10) is a Indisulam (HY-13650) derivative, and inhibits the migration of gastric cancer cells. WXM-1-170 attenuates PI3K/AKT/GSK-3β/β-catenin signaling pathway[1].

Product Specifications

UNSPSC

12352005

Target

PI3K

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/wxm-1-170.html

Solubility

10 mM in DMSO

Smiles

N#CC1=CC(S(=O)(N(C2=C3NC=C(C3=CC=C2)Cl)CC(N)=O)=O)=CC=C1

Molecular Formula

C17H13ClN4O3S

Molecular Weight

388.83

References & Citations

[1]Hou C, et al. Subtle structural alteration in indisulam switches the molecular mechanisms for the inhibitory effect on the migration of gastric cancer cells. Biomed Pharmacother. 2024;172:116259.