Antifungal agent 115
Antifungal agent 115 (compound 8n) is a non-competitive chitin synthase (CHS) inhibitor with an IC50 of 93 μM. Antifungal agent 115 demonstrates good selectivity and broad-spectrum antifungal activity, exhibiting significant efficacy against drug-resistant fungi. Antifungal agent 115 can be utilized in fungi infection research[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antifungal-agent-115.html
Smiles
O=C(C1CCN(CC(NC2=CC(NC3=O)=C(C=C2)CC43C(NCC4)=O)=O)CC1)NC5=CC=C([N+]([O-])=O)C=C5C
Molecular Formula
C27H30N6O6
Molecular Weight
534.56
References & Citations
[1]Long Y, et al. Design and synthesis of spiro[pyrrolidine-3,3'-quinoline]-2,2'-dione derivatives as novel antifungal agents targeting chitin synthase. Eur J Med Chem. 2024 Sep 18;279:116895.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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