N-Methylhistamine (dihydrochloride)
N-Methylhistamine (Nα-Methylhistamine) dihydrochloride is a potent agonist of the histamine H3 receptor, exhibiting significant implications in the diagnosis and management of mastocytosis. N-Methylhistamine (dihydrochloride) also serves as a biomarker for assessing mast cell accumulation in clinical evaluations.
Product Specifications
CAS Number
[16503-22-3]
Product Name Alternative
Nα-Methylhistamine (dihydrochloride)
UNSPSC
12352005
Hazard Statement
H302, H315, H318, H335
Target
Histamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/n-methylhistamine-dihydrochloride.html
Concentration
10mM
Purity
99.99
Solubility
DMSO : 4.17 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
CNCCC1=CN=CN1.Cl.Cl
Molecular Formula
C6H13Cl2N3
Molecular Weight
198.09
Precautions
H302, H315, H318, H335
References & Citations
[1]Urinary N-methylhistamine as an indicator of bone marrow involvement in mastocytosis
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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