Metoprolol (succinate) (Standard)

Metoprolol (succinate) (Standard) is the analytical standard of Metoprolol (succinate) . This product is intended for research and analytical applications. Metoprolol succinate is an orally active, selective β1-adrenoceptor antagonist. Metoprolol succinate shows anti-inflammation, antitumor and anti-angiogenic properties[1][2][3].

Product Specifications

CAS Number

[98418-47-4]

UNSPSC

12352005

Hazard Statement

H370

Target

Adrenergic Receptor; Apoptosis; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; GPCR/G Protein; Neuronal Signaling; Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cardiovascular Disease; Endocrinology; Cancer

Assay Protocol

https://www.medchemexpress.com/metoprolol-succinate-standard.html

Purity

99.94

Smiles

OC(CNC(C)C)COC1=CC=C(CCOC)C=C1.OC(CNC(C)C)COC2=CC=C(CCOC)C=C2.OC(CCC(O)=O)=O

Molecular Formula

C34H56N2O10

Molecular Weight

652.82

Precautions

H370

References & Citations

[1]Ulleryd MA, et al. Metoprolol reduces proinflammatory cytokines and atherosclerosis in ApoE-/- mice. Biomed Res Int. 2014;2014:548783.|[2]Wang D, et al. Carvedilol has stronger anti-inflammation and anti-virus effects than metoprolol in murine model with coxsackievirus B3-induced viral myocarditis. Gene. 2014 Sep 1;547 (2) :195-201.|[3]Hajatbeigi B, et al. Cytotoxicity of Metoprolol on Leukemic Cells in Vitro. IJBC 2018; 10 (4) : 124-129.|[4]Su Q, et al. Effect of metoprolol on myocardial apoptosis and caspase-9 activation after coronary microembolization in rats. Exp Clin Cardiol. 2013 Spring;18 (2) :161-5.