OT-551
OT-551 is a NF-κB inhibitor with antioxidant and anti-inflammatory effects. OT-551 has the potential for retinal diseases research[1][2].
Product Specifications
CAS Number
627085-15-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
NF-κB
Type
Reference compound
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ot-551.html
Solubility
10 mM in DMSO
Smiles
CC1(C)CC(OC(C2CC2)=O)CC(C)(C)N1O.[H]Cl
Molecular Formula
C13H24ClNO3
Molecular Weight
277.79
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Masaki Tanito, et al. Protection of retinal pigment epithelium by OT-551 and its metabolite TEMPOL-H against light-induced damage in rats. Exp Eye Res. 2010 Jul;91 (1) :111-4. |[2]S. A. Mousa, et al. Anti-Angiogenesis Efficacy of the Novel NF-B and Oxidative Stress Inhibitor, OT-551. ARVO Annual Meeting Abstract.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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