Schisandrin C

Schisandrin C (Schizandrin-C) is a phytochemical lignan isolated from Schizandra chinensis[1]. Schisandrin C has diverse biological activities, including anticancer, anti-inflammatory and antioxidant effects. Schisandrin C can be used for cancer, alzheimer’s disease, and liver diseases research[2][3]. Schisandrin C induces cell apoptosis[1].

Product Specifications

CAS Number

[61301-33-5]

Product Name Alternative

Schizandrin-C; Wuweizisu-C

UNSPSC

12352005

Hazard Statement

H302, H410

Target

Apoptosis

Type

Natural Products

Related Pathways

Apoptosis

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Schisandrin-C.html

Concentration

10mM

Purity

99.95

Solubility

DMSO : 8.33 mg/mL (ultrasonic)

Smiles

[H][C@@]([C@](C)([H])C1)(C)CC2=CC3=C(C(OC)=C2C4=C1C=C5OCOC5=C4OC)OCO3

Molecular Formula

C22H24O6

Molecular Weight

384.42

Precautions

H302, H410

References & Citations

[1]Park C, et al. Induction of G1 arrest and apoptosis by schisandrin C isolated from Schizandra chinensis Baill in human leukemia U937 cells. Int J Mol Med. 2009 Oct;24 (4) :495-502.|[2]Oh SY, et al. Anti-inflammatory effects of gomisin N, gomisin J, and schisandrin C isolated from the fruit of Schisandra chinensis. Biosci Biotechnol Biochem. 2010;74 (2) :285-91.|[3]Xin Mao, et al.Schisandrin C Ameliorates Learning and Memory Deficits by Aβ 1-42 -induced Oxidative Stress and Neurotoxicity in Mice. Phytother Res. 2015 Sep;29 (9) :1373-1380.