Odetiglucan
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response[1][2].
Product Specifications
CAS Number
53238-80-5
Product Name Alternative
BTH 1677; Imprime PGG
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Toll-like Receptor (TLR)
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/odetiglucan.html
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 100 mg/mL (ultrasonic)
Smiles
OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O[C@H]2[C@H](O)[C@@H](O[C@H]3[C@H](O)[C@@H](O[H])[C@H](O)[C@@H](CO)O3)[C@H](O)[C@@H](CC[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O[H])[C@H]4O)O2)[C@@H]1O.[x].[y].[x=y~10;z~4;n~4;(x+y+z+1)xn~100].[(C6H10O5)n(H2O);n=100;M=16kDa].[z]
Precautions
H315, H319, H335
References & Citations
[1]WHO Drug Information. International Nonproprietary Names for Pharmaceutical|[2]Stacy K Thomas, et al. Kupffer cells prevent pancreatic ductal adenocarcinoma metastasis to the liver in mice. Nat Commun. 2023 Oct 10;14 (1) :6330.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Available Sizes
Frequently Asked Questions
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