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Tolonidine

Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties[1].

Product Specifications

CAS Number

4201-22-3

UNSPSC

12352005

Hazard Statement

H315-H319-H320

Target

Angiotensin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/tolonidine.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CC1=CC=C(NC2=NCCN2)C(Cl)=C1

Molecular Formula

C10H12ClN3

Molecular Weight

209.68

Precautions

P264-P280-P302+P352-P305+P351+P338-P362

References & Citations

[1]Cosnier D, et al. Pharmacological properties of 2- (2-chloro-p-toluidino) -2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis. Arzneimittelforschung. 1975 Nov;25 (11) :1802-6.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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