Tolonidine
Tolonidine is a derivative of imidazoline. Tolonidine is orally active and has been shown to possess hypotensive and antihypertensive properties[1].
Product Specifications
CAS Number
4201-22-3
UNSPSC
12352005
Hazard Statement
H315-H319-H320
Target
Angiotensin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/tolonidine.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CC1=CC=C(NC2=NCCN2)C(Cl)=C1
Molecular Formula
C10H12ClN3
Molecular Weight
209.68
Precautions
P264-P280-P302+P352-P305+P351+P338-P362
References & Citations
[1]Cosnier D, et al. Pharmacological properties of 2- (2-chloro-p-toluidino) -2-imidazoline-nitrate (tolonidine), a new antihypertensive agent. II. Action on cardiac contraction, circulatory parameters, autonomic receptors and diuresis. Arzneimittelforschung. 1975 Nov;25 (11) :1802-6.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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