Phenylhydroquinone
Phenylhydroquinone (PHQ) is an orally active thymic atrophy inducer which can up-regulate apoptosis through activation of p53. PHQ can be used for research of thymic atrophy[1].
Product Specifications
CAS Number
1079-21-6
Product Name Alternative
2-Phenylhydroquinone
UNSPSC
12352005
Hazard Statement
H315, H319, H335
Target
ERK; MDM-2/p53; p38 MAPK
Type
Reference compound
Related Pathways
Apoptosis; MAPK/ERK Pathway; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/phenylhydroquinone.html
Purity
99.21
Solubility
10 mM in DMSO
Smiles
OC1=CC(C2=CC=CC=C2)=C(O)C=C1
Molecular Formula
C12H10O2
Molecular Weight
186.21
Precautions
H315, H319, H335
References & Citations
[1]Nakata Y, et al. Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway. J Toxicol Sci. 2013;38 (3) :325-35.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2
Available Sizes
Frequently Asked Questions
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