Phenylhydroquinone

Phenylhydroquinone (PHQ) is an orally active thymic atrophy inducer which can up-regulate apoptosis through activation of p53. PHQ can be used for research of thymic atrophy[1].

Product Specifications

CAS Number

[1079-21-6]

Product Name Alternative

2-Phenylhydroquinone

UNSPSC

12352005

Hazard Statement

H315, H319, H335

Target

ERK; MDM-2/p53; p38 MAPK

Type

Reference compound

Related Pathways

Apoptosis; MAPK/ERK Pathway; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/phenylhydroquinone.html

Purity

99.21

Solubility

10 mM in DMSO

Smiles

OC1=CC(C2=CC=CC=C2)=C(O)C=C1

Molecular Formula

C12H10O2

Molecular Weight

186.21

Precautions

H315, H319, H335

References & Citations

[1]Nakata Y, et al. Phenylhydroquinone induces loss of thymocytes through cell cycle arrest and apoptosis elevation in p53-dependent pathway. J Toxicol Sci. 2013;38 (3) :325-35.