ARRY-380 (analog)
ARRY-380 analog (Compound PCM-0095494) is an ARRY-380 (HY-16069) analog. ARRY-380 analog activates caspases 3 and caspases 8. ARRY-380 analog inhibits Salmonella replication in cells[1].
Product Specifications
CAS Number
[937265-83-3]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-Kinase/protease
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/ARRY-380-analog.html
Purity
99.19
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(CCNCC1=CC=C(C2=CC3=C(NC4=CC=C(OC5=CC6=NC=NN6C=C5)C(C)=C4)N=CN=C3C=C2)O1)(C)=O
Molecular Formula
C29H27N7O4S
Molecular Weight
569.63
Precautions
H315, H319
References & Citations
[1]Ohad GAL-MOR, et al. Treatment of infections caused by intracellular pathogens. WO 2025/004049 A1. WIPO (PCT) . 2024-06-28.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 1
Isoform
Caspase 3; Caspase 8
Available Sizes
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