OB-1
OB-1 is a stomatin-like protein-3 (STOML3) oligomerization blocker. OB-1 is an effective inhibitor of the self-association of Stomatin, STOML1 and STOML2, but not podocin[1].
Product Specifications
CAS Number
300803-69-4
UNSPSC
12352005
Target
SPFH Protein Superfamily
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ob-1.html
Purity
99.12
Solubility
DMSO : 12.73 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(C2=CC=CC=C2)OC3=CC=C(OC4=C([N+]([O-])=O)N=CN4C)C=C13)OCC
Molecular Formula
C21H17N3O6
Molecular Weight
407.38
References & Citations
[1]Wetzel C, et al. Small-molecule inhibition of STOML3 oligomerization reverses pathological mechanical hypersensitivity. Nat Neurosci. 2017 Feb;20 (2) :209-218.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Stomatin
Available Sizes
Frequently Asked Questions
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