KT203
KT203 is a potent and selective inhibitor of α/β-hydrolase domain containing 6 (ABHD6), with an IC50 of 0.31 nM in Neuro2A cells[1].
Product Specifications
CAS Number
[1402612-64-9]
UNSPSC
12352005
Target
MAGL
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/kt203.html
Concentration
10mM
Purity
99.86
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(N1C(CCCC1)CC2=CC=CC=C2)N3N=NC(C4=CC=C(C=C4)C5=CC=CC(C(O)=O)=C5)=C3
Molecular Formula
C28H26N4O3
Molecular Weight
466.53
References & Citations
[1]Hsu KL, et al. Discovery and optimization of piperidyl-1,2,3-triazole ureas as potent, selective, and in vivo-active inhibitors of α/β-hydrolase domain containing 6 (ABHD6) . J Med Chem. 2013 Nov 14;56 (21) :8270-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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