Nav1.8-IN-15
Nav1.8-IN-15 (compound 6) is a potent Nav1.8 inhibitor. Nav1.8-IN-15 shows analgesic effect. Nav1.8-IN-15 has the potential for the research of chronic pain[1].
Product Specifications
CAS Number
[524061-69-6]
UNSPSC
12352005
Target
Sodium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nav1-8-in-15.html
Smiles
O=S(C1=CC=CC(S(=O)(C2=CC=C(Cl)C=C2)=O)=C1)(NC[C@@]3(CC4C5)C[C@H](C4)C[C@H]5C3)=O
Molecular Formula
C23H26ClNO4S2
Molecular Weight
480.04
References & Citations
[1]Song C, et al. Identification of N- (((1S,3R,5S) -adamantan-1-yl) methyl) -3- ((4-chlorophenyl) sulfonyl) benzenesulfonamide as novel Nav1.8 inhibitor with analgesic profile. Bioorg Med Chem Lett. 2024 Jun 27;110:129862.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Nav1.8
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