Nav1.8-IN-15

Nav1.8-IN-15 (compound 6) is a potent Nav1.8 inhibitor. Nav1.8-IN-15 shows analgesic effect. Nav1.8-IN-15 has the potential for the research of chronic pain[1].

Product Specifications

CAS Number

[524061-69-6]

UNSPSC

12352005

Target

Sodium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/nav1-8-in-15.html

Smiles

O=S(C1=CC=CC(S(=O)(C2=CC=C(Cl)C=C2)=O)=C1)(NC[C@@]3(CC4C5)C[C@H](C4)C[C@H]5C3)=O

Molecular Formula

C23H26ClNO4S2

Molecular Weight

480.04

References & Citations

[1]Song C, et al. Identification of N- (((1S,3R,5S) -adamantan-1-yl) methyl) -3- ((4-chlorophenyl) sulfonyl) benzenesulfonamide as novel Nav1.8 inhibitor with analgesic profile. Bioorg Med Chem Lett. 2024 Jun 27;110:129862.