DSLET

DSLET ([D-Ser2, Leu5, Thr6]-enkephalin) is a highly specific agonist of the δ-receptor. DSLET is an enkephalin-related peptide selectively bound to the δ opioid receptor[1][2].

Product Specifications

CAS Number

[75644-90-5]

Product Name Alternative

[D-Ser2, Leu5, Thr6]-enkephalin

UNSPSC

12352209

Target

Opioid Receptor

Type

Peptides

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dslet.html

Solubility

10 mM in DMSO

Smiles

C[C@@H](O)[C@@H](C(O)=O)NC([C@H](CC(C)C)NC([C@@H](NC(CNC([C@@H](CO)NC([C@@H](N)CC1=CC=C(O)C=C1)=O)=O)=O)CC2=CC=CC=C2)=O)=O

Molecular Formula

C33H46N6O10

Molecular Weight

686.75

References & Citations

[1]J L Nano, et al. Characterization of delta-opioid receptors and effect of enkephalins on IRD 98 rat epithelial intestinal cell line. Pflugers Arch. 2000 Mar;439 (5) :547-54.|[2]C S Goodchild, et al. Antinociception by intrathecal midazolam involves endogenous neurotransmitters acting at spinal cord delta opioid receptors. Br J Anaesth. 1996 Dec;77 (6) :758-63.