DENND1A, Human (His-SUMO)

The DENND1A protein is a guanine nucleotide exchange factor (GEF) that coordinates clathrin-mediated endocytosis through activation of RAB35. It catalyzes the conversion of inactive GDP-bound RAB35 into its active GTP-bound state, regulating synaptic vesicle dynamics and other processes. DENND1A Protein, Human (His-SUMO) is the recombinant human-derived DENND1A, expressed by E. coli , with N-SUMO, N-6*His labeled tag. The total length of DENND1A Protein, Human (His-SUMO) is 559 a.a.,

MGSRIKQNPE TTFEVYVEVA YPRTGGTLSD PEVQRQFPED YSDQEVLQTL TKFCFPFYVD SLTVSQVGQN FTFVLTDIDS KQRFGFCRLS SGAKSCFCIL SYLPWFEVFY KLLNILADYT TKRQENQWNE LLETLHKLPI PDPGVSVHLS VHSYFTVPDT RELPSIPENR NLTEYFVAVD VNNMLHLYAS MLYERRILII CSKLSTLTAC IHGSAAMLYP MYWQHVYIPV LPPHLLDYCC APMPYLIGIH LSLMEKVRNM ALDDVVILNV DTNTLETPFD DLQSLPNDVI SSLKNRLKKV STTTGDGVAR AFLKAQAAFF GSYRNALKIE PEEPITFCEE AFVSHYRSGA MRQFLQNATQ LQLFKQFIDG RLDLLNSGEG FSDVFEEEIN MGEYAGSDKL YHQWLSTVRK GSGAILNTVK TKANPAMKTV YKFAKDHAKM GIKEVKNRLK QKDIAENGCA PTPEEQLPKT APSPLVEAKD PKLREDRRPI TVHFGQVRPP RPHVVKRPKS NIAVEGRRTS VPSPEQNTIA TPATLHILQK SITHFAAKFP TRGWTSSSH