Samatasvir
Samatasvir (IDX71) is a potent, orally active NS5A inhibitor of HCV replication. Samatasvir is effective and selective against infectious HCV and replicons, with EC50s falling within a tight range of 2 to 24 pM in genotype 1 through 5 replicons[1].
Product Specifications
CAS Number
1312547-19-5
Product Name Alternative
IDX719; IDX18719
UNSPSC
12352005
Target
HCV; HCV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/samatasvir.html
Concentration
10mM
Purity
99.39
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(OC)N[C@H](C1=CC=CC=C1)C(N2[C@H](C3=NC=C(C4=CC=C(C5=CSC6=C5SC=C6C7=CC=C8N=C([C@H]9N(C([C@@H](NC(OC)=O)C(C)C)=O)CCC9)NC8=C7)C=C4)N3)CCC2)=O
Molecular Formula
C47H48N8O6S2
Molecular Weight
885.06
References & Citations
[1]Bilello JP, et al. In vitro activity and resistance profile of samatasvir, a novel NS5A replication inhibitor of hepatitis C virus. Antimicrob Agents Chemother. 2014;58 (8) :4431-4442.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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