PFI-7
Product Specifications
UNSPSC Description
PFI-7 is a probe, which binds to human GID4 (KD is 79 nM), and antagonizes the binding of Pro/N-degrons. PFI-7 can be utilized in C-terminal to LisH (CTLH) complex research and development of targeted protein degradation[1].
Target Antigen
E1/E2/E3 Enzyme
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pfi-7.html
Smiles
O=C(N[C@@H]1CC[C@H](C2=NC(C=CC=C3)=C3N2)CC1)CNCC4=CC5=C(C=CC=C5)N4
Molecular Weight
401.50
References & Citations
[1]Owens DDG, et al., A chemical probe to modulate human GID4 Pro/N-degron interactions. Nat Chem Biol. 2024 May 21.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-D2259/PFI-7-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-D2259/
Clinical Information
No Development Reported
CAS Number
2910938-58-6
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal NELL2 Antibody (055) [Janelia Fluor 549]](https://cdn.genprice.uk/genprice/genprice4.png)
