δ-Theraphotoxin-Hm1a toxin
δ-Theraphotoxin-Hm1a toxin is a selective Nav1.1 activator. δ-Theraphotoxin-Hm1a toxin elicits pain and touch sensitivity. δ-Theraphotoxin-Hm1a toxin can be used for the research of irritable bowel syndrome[1].
Product Specifications
UNSPSC
12352209
Target
Sodium Channel
Type
Peptides
Related Pathways
Membrane Transporter/Ion Channel
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/δ-theraphotoxin-hm1a-toxin.html
Solubility
10 mM in DMSO
Smiles
O=C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC(C)C)C(N[C@H]2CO)=O)=O)=O)=O)NC3=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC4=CC=C(C=C4)O)C(N[C@@H](CC(C)C)C(N[C@@H](CC5=CC=CC=C5)C(NCC(NCC(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CC6=CNC7=CC=CC=C67)C(N[C@@H](CCCCN)C(N[C@H]8CC9=CC=C(C=C9)O)=O)=O)=O)=O)=O)=O)NC2=O)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H]([C@H](O)C)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@H]3CSSC[C@@H](C(N[C@@H](C)C(N[C@@H](CC%10=CNC%11=CC=CC=C%10%11)C(N[C@@H](CC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H](CC%12=CC=CC=C%12)C(N[C@@H](CO)C(N)=O)=O)=O)=O)=O)=O)=O)=O)NC8=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(O)=O)N
Molecular Formula
C170H240N48O53S6
Molecular Weight
3996.40
References & Citations
[1]Osteen JD, et al. Selective spider toxins reveal a role for the Nav1.1 channel in mechanical pain. Nature. 2016 Jun 23;534 (7608) :494-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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