GPR183-IN-1
GPR183-IN-1 (compound 15) is a potent and orally activity GPR183 inhibitor. GPR183-IN-1 inhibits Ca2+ mobilization with an IC50 value of 39.97 nM. GPR183-IN-1 has the potential for the research of cancer, autoimmune diseases, pain, and osteoporosis[1].
Product Specifications
CAS Number
2924063-70-5
UNSPSC
12352005
Target
EBI2/GPR183
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/gpr183-in-1.html
Smiles
O=C(N1CCN(CC1)C2COC2)/C=C/C3=CC=C(C=C3)Br
Molecular Formula
C16H19BrN2O2
Molecular Weight
351.24
References & Citations
[1]JianFei Xi, et al. Compounds and their use as GPR183 inhibitors. CN118201911A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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