Vasicinol
Vasicinol is a reversible inhibitor of sucrase (IC50: 250 μM) . Vasicinol is a HbF inducer. Vasicinol also inhibits Angiotensin-converting Enzyme (ACE) . Vasicinol is apyrroquinazoline alkaloid that can be isolated from Adhatoda vasica[1][2].
Product Specifications
CAS Number
5081-51-6
Product Name Alternative
6-Hydroxypeganine
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Angiotensin-converting Enzyme (ACE)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/vasicinol.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1CCN2C1=NC3=C(C=C(O)C=C3)C2
Molecular Formula
C11H12N2O2
Molecular Weight
204.23
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Gao H, et al. Inhibitory effect on α-glucosidase by Adhatoda vasica Nees. Food Chem. 2008 Jun 1;108 (3) :965-72.|[2]Tehreem S, et al. A UPLC-DAD-Based Bio-Screening Assay for the Evaluation of the Angiotensin Converting Enzyme Inhibitory Potential of Plant Extracts and Compounds: Pyrroquinazoline Alkaloids from Adhatoda vasica as a Case Study. Molecules. 2021 Nov 18;26 (22) :6971.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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