Cefpimizole

Cefpimizole (U-63196E) is a broad-spectrum cephalosporin antibiotic. Cefpimizole inhibits many Ampicillin (HY-B0522) -resistant bacteria, and is active against gram-negative species. Cefpimizole augments phagocytosis of macrophages and neutrophils[1][2].

Product Specifications

CAS Number

[84880-03-5]

Product Name Alternative

U-63196E; AC-1370

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/cefpimizole.html

Smiles

[O-]C(C1=C(C[N+]2=CC=C(CCS(=O)(O)=O)C=C2)CS[C@@]([C@@H]3NC([C@@H](C4=CC=CC=C4)NC(C5=C(N=CN5)C(O)=O)=O)=O)([H])N1C3=O)=O

Molecular Formula

C28H26N6O10S2

Molecular Weight

670.67

References & Citations

[1]Neu HC, et al. In vitro activity and beta-lactamase stability of U-63196E, a novel cephalosporin. Antimicrob Agents Chemother. 1983 Sep;24 (3) :375-82.|[2]Ohnishi H, et al. Effects of AC-1370, a new semisynthetic cephalosporin, on phagocyte functions. Antimicrob Agents Chemother. 1983 Jun;23 (6) :874-80.