RIP3 (phospho-Ser227) rabbit pAb
The product of this gene is a member of the receptor-interacting protein (RIP) family of serine/threonine protein kinases, and contains a C-terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor-I signaling complex, and can induce apoptosis and weakly activate the NF-kappaB transcription factor. [provided by RefSeq, Jul 2008],
Product Specifications
Background
UniProt
Q9Y572
Swiss Prot
Q9Y572
Reactivity
Human
Immunogen
Synthesized phosho peptide around human RIP3 (Ser227)
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000
Molecular Weight
56-70kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
56-70kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol . Nucleus . Mainly cytoplasmic. Present in the nucleus in response to influenza A virus (IAV) infection. .
Other Product Names
Receptor-interacting serine/threonine-protein kinase 3 (EC 2.7.11.1) (RIP-like protein kinase 3) (Receptor-interacting protein 3) (RIP-3)
Gene ID (Human)
11035
Available Sizes
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
