DR2313
DR2313 is a potent, selective, competitive and brain-penetrant inhibitor of poly (ADP-ribose) polymerase (PARP), with IC50s of 0.20 μM and 0.24 μM for PARP-1 and PARP-2, respectively. DR2313 exhibits neuroprotective effects on ischemic injuries in vitro and in vivo[1][2].
Product Specifications
CAS Number
284028-90-6
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/dr2313.html
Purity
99.66
Solubility
DMSO : 12.5 mg/mL (ultrasonic) |H2O : ≥ 100 mg/mL
Smiles
O=C1C(CSCC2)=C2NC(C)=N1
Molecular Formula
C8H10N2OS
Molecular Weight
182.25
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PARP1; PARP2
Available Sizes
Frequently Asked Questions
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