Efdamrofusp alfa

Efdamrofusp alfa is a bispecific fusion protein. Efdamrofusp alfa is capable of neutralizing both VEGF isoforms and C3b/C4b. Efdamrofusp alfa can be used for the research of neovascular age-related macular degeneration (nAMD) and other complement-related ocular conditions[1].

Product Specifications

CAS Number

[2375661-82-6]

Product Name Alternative

IBI302

UNSPSC

12352203

Target

VEGFR

Type

Inhibitory Antibodies

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/efdamrofusp-alfa.html

Purity

99.89

Solubility

10 mM in DMSO

Smiles

[Efdamrofuspalfa]

Molecular Weight

(140.4 kDa)

References & Citations

[1]Shiqi Yang, et al. Targeting C3b/C4b and VEGF with a bispecific fusion protein optimized for neovascular age-related macular degeneration therapy. Sci Transl Med. 2022 Jun;14 (647) :eabj2177.