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RIP2 Kinase Inhibitor 3

Product Specifications

UNSPSC Description

RIP2 Kinase Inhibitor 3 is a highly potent and selective inhibitor of receptor interacting protein-2 (RIP2) Kinase with an IC50 of 1 nM [1].

Target Antigen

RIP kinase

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rip2-kinase-inhibitor-3.html

Purity

99.82

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=S(C1=C(OC)C=C(N=CC=C2NC3=NNC(C)=C3C)C2=C1)(C(C)(C)C)=O

Molecular Weight

388.48

References & Citations

[1]Haile PA, et al. Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel. ACS Med Chem Lett. 2018 Sep 26;9(10):1039-1044.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-112907/RIP2-Kinase-Inhibitor-3-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-112907/RIP2-Kinase-Inhibitor-3-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1398053-50-3

Available Sizes

Curated Selection

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