RIP2 Kinase Inhibitor 3

RIP2 Kinase Inhibitor 3 is a highly potent and selective inhibitor of receptor interacting protein-2 (RIP2) Kinase with an IC50 of 1 nM [1].

Product Specifications

CAS Number

[1398053-50-3]

UNSPSC

12352005

Target

RIP kinase

Type

Reference compound

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/rip2-kinase-inhibitor-3.html

Purity

99.76

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

O=S(C1=C(OC)C=C(N=CC=C2NC3=NNC(C)=C3C)C2=C1)(C(C)(C)C)=O

Molecular Formula

C19H24N4O3S

Molecular Weight

388.48

References & Citations

[1]Haile PA, et al. Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel. ACS Med Chem Lett. 2018 Sep 26;9 (10) :1039-1044.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture and light)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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