RIP2 Kinase Inhibitor 3
RIP2 Kinase Inhibitor 3 is a highly potent and selective inhibitor of receptor interacting protein-2 (RIP2) Kinase with an IC50 of 1 nM [1].
Product Specifications
CAS Number
[1398053-50-3]
UNSPSC
12352005
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rip2-kinase-inhibitor-3.html
Purity
99.76
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=S(C1=C(OC)C=C(N=CC=C2NC3=NNC(C)=C3C)C2=C1)(C(C)(C)C)=O
Molecular Formula
C19H24N4O3S
Molecular Weight
388.48
References & Citations
[1]Haile PA, et al. Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel. ACS Med Chem Lett. 2018 Sep 26;9 (10) :1039-1044.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
133283-FITC 100 µL
SH2D1A (SH2 Domain-containing Protein 1A, Duncan Disease SH2-protein, Signaling Lymphocytic Activation Molecule-associated Protein, SLAM-associated Protein, T-cell Signal Transduction Molecule SAP, DSHP, SAP, FLJ18687, FLJ92177) (FITC)
Sign In for Pricing
View Details 
abx384721 96 Tests
Human Dual Specificity Protein Kinase CLK3 (CLK3) ELISA Kit
Sign In for Pricing
View Details 