RIP2 Kinase Inhibitor 3
RIP2 Kinase Inhibitor 3 is a highly potent and selective inhibitor of receptor interacting protein-2 (RIP2) Kinase with an IC50 of 1 nM [1].
Product Specifications
CAS Number
[1398053-50-3]
UNSPSC
12352005
Target
RIP kinase
Type
Reference compound
Related Pathways
Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/rip2-kinase-inhibitor-3.html
Purity
99.76
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
O=S(C1=C(OC)C=C(N=CC=C2NC3=NNC(C)=C3C)C2=C1)(C(C)(C)C)=O
Molecular Formula
C19H24N4O3S
Molecular Weight
388.48
References & Citations
[1]Haile PA, et al. Identification of Quinoline-Based RIP2 Kinase Inhibitors with an Improved Therapeutic Index to the hERG Ion Channel. ACS Med Chem Lett. 2018 Sep 26;9 (10) :1039-1044.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
C2256-65A-APC 100 µL
CD5L, CT (CD5-Like, Sp-alpha, AIM) (APC) discontinued
Sign In for Pricing
View Details ELI-24958h 96 Tests
Human Calcium-binding protein 2,CABP2 ELISA KIT
Sign In for Pricing
View Details 
MBS7039579-01 0.02 mg
Recombinant Rhizobium sp. Uncharacterized protein y4cB (NGR_a00120)
Sign In for Pricing
View Details