6PPD

6PPD is a rubber antioxidant that scavenges ozone, forming nitroxyl radicals. 6PPD exposure decreases hatchability, lowered autonomous movement, reduces body length in zebrafish embryos and causes deformities. 6PPD also produces oxidative stress in zebrafish embryos[1].

Product Specifications

CAS Number

[793-24-8]

UNSPSC

12352005

Hazard Statement

H302, H317, H410

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/6ppd.html

Purity

99.44

Solubility

DMSO : 200 mg/mL (ultrasonic) |H2O : < 0.1 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CC(C)CC(NC1=CC=C(NC2=CC=CC=C2)C=C1)C

Molecular Formula

C18H24N2

Molecular Weight

268.40

Precautions

H302, H317, H410

References & Citations

[1]Peng W, et al. Exposure to N- (1,3-dimethylbutyl) -N'-phenyl-p-phenylenediamine (6PPD) affects the growth and development of zebrafish embryos/larvae. Ecotoxicol Environ Saf. 2022 Mar 1;232:113221.