DPP-4-IN-12
DPP-4-IN-12 (compound 46) is a potent DPP-4 inhibitor with IC50 value of 2 nM. DPP-4-IN-12 can be used in the study of type 2 diabetes[1].
Product Specifications
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/dpp-4-in-12.html
Smiles
CC1=C(C(N=C(N1C(CN2CC3=CN(S(=O)(C)=O)N=C3C2)=O)N)C4=CC(F)=C(C=C4)F)C(O)=O
Molecular Formula
C20H20F2N6O5S
Molecular Weight
494.47
References & Citations
[1]Mobeen B, et al. Discovery of the selective and nanomolar inhibitor of DPP-4 more potent than sitagliptin by structure-guided rational design. Eur J Med Chem. 2024 Sep 5;279:116834.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-4
Frequently Asked Questions
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