1E7-03
1E7-03, a low MW tetrahydroquinoline derivative targeting protein phosphatase-1, can inhibit HIV-1 transcription[1].
Product Specifications
CAS Number
[1565845-92-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
HIV; Phosphatase
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/1e7-03.html
Purity
95.07
Solubility
DMSO : 20.83 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=C(CC/C2=C\C3=CC=C(OC)C(OC)=C3)C2=NC4=CC=CC=C14)OC(C)C(NC(NCC)=O)=O
Molecular Formula
C28H29N3O6
Molecular Weight
503.55
Precautions
H302, H315, H319, H335
References & Citations
[1]Ammosova T, et al. 1E7-03, a low MW compound targeting host protein phosphatase-1, inhibits HIV-1 transcription. Br J Pharmacol. 2014;171 (22) :5059-5075.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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