Human FGF-8b (Fibroblast Growth Factor-8b)

<strong>Human FGF-8b (Fibroblast Growth Factor-8b)</strong>_x000D_ <strong>Catalog number:</strong> B2018710_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~21 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> FGF-8b, Fibroblast Growth Factor 8b_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Ruohola JK, Viitanen TP, Valve EM, Seppänen JA, Loponen NT, Keskitalo JJ, Lakkakorpi PT, Härkönen PL. Enhanced invasion and tumor growth of fibroblast growth factor 8b-overexpressing MCF-7 human breast cancer cells Cancer Res. 2001 May 15;61(10):4229-37._x000D_ 2: Nilsson EM, Brokken LJ, Narvi E, Kallio MJ, Härkönen PL. Identification of fibroblast growth factor-8b target genes associated with early and late cell cycle events in breast cancer cells Mol Cell Endocrinol. 2012 Jul 6;358(1):104-15._x000D_ 3: Mark RJ, Fuson KS, Keane-Lazar K, May PC. Fibroblast growth factor-8 protects cultured rat hippocampal neurons from oxidative insult Brain Res. 1999 May 29;830(1):88-93._x000D_ 4: Valta MP, Tuomela J, Vuorikoski H, Loponen N, Väänänen RM, Pettersson K, Väänänen HK, Härkönen PL. FGF-8b induces growth and rich vascularization in an orthotopic PC-3 model of prostate cancer J Cell Biochem. 2009 Jul 1;107(4):769-84._x000D_ 5: Elo TD, Valve EM, Seppänen JA, Vuorikoski HJ, Mäkelä SI, Poutanen M, Kujala PM, Härkönen PL. Stromal activation associated with development of prostate cancer in prostate-targeted fibroblast growth factor 8b transgenic mice Neoplasia. 2010 Nov;12(11):915-27._x000D_ 6: Valta MP, Hentunen T, Qu Q, Valve EM, Harjula A, Seppänen JA, Väänänen HK, Härkönen PL. Regulation of osteoblast differentiation: a novel function for fibroblast growth factor 8 Endocrinology. 2006 May;147(5):2171-82._x000D_ 7: Nilsson EM, Brokken LJ, Härkönen PL. Fibroblast growth factor 8 increases breast cancer cell growth by promoting cell cycle progression and by protecting against cell death Exp Cell Res. 2010 Mar 10;316(5):800-12._x000D_ 8: Tanaka A, Furuya A, Yamasaki M, Hanai N, Kuriki K, Kamiakito T, Kobayashi Y, Yoshida H, Koike M, Fukayama M. High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8 Cancer Res. 1998 May 15;58(10):2053-6._x000D_ 9: Lin X, Song L, He D, Zeng X, Wu J, Luo W, Yang Q, Wang J, Wang T, Cai J, Lin Y, Lai F, Peng W, Wu X. An FGF8b-mimicking peptide with potent antiangiogenic activity Mol Med Rep. 2017 Jul;16(1):894-900._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/11406643">10: Valve EM, Nevalainen MT, Nurmi MJ, Laato MK, Martikainen PM, Härkönen PL. Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer Lab Invest. 2001 Jun;81(6):815-26. </a>_x000D_ _x000D_ <strong>Products Related to Human FGF-8b (Fibroblast Growth Factor-8b) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>