Anti-Calcineurin A (Catalytic) Antibody

Rabbit Polyclonal Antibody specific to Calcineurin A (Catalytic)

Product Specifications

Product Name Alternative

EC 3.1.3.16, CAM-PRP catalytic subunit, Calmodulin-dependent calcineurin A subunit α isoform

Gene Name

PPP3CA

Gene ID

5530

NCBI Gene ID

Accession Number

NP_000935

Host

Rabbit

Reactivity

Human, Mouse, Rat, Rabbit, Hamster, Bovine, Canine

Immunogen

Synthetic peptide corresponding to aa 264-283 of human Calcineurin A conjugated to KLH. This sequence is identical in rat and mouse calcineurin A.

Target Antigen

Serine/threonine-protein phosphatase 2B catalytic subunit α isoform

Target

Calcineurin A (Catalytic)

Clonality

Polyclonal

Type

Antibody

Applications

WB, IP

Field of Research

Neuroscience

Purification Method

Purified by protein A affinity chromatography

Concentration

Lot Specific

Dilution

Dilute in PBS or medium that is identical to that used in the assay system.

Format

Purified

Form

Liquid

Buffer

Phosphate Buffered Saline

Additionnal Information

Immunoblotting: Use at 1-5ug/mL. A band of ~61kDa is detected. <br><br>These are recommended concentrations. <br><br>Endusers should determine optimal concentrations for their application.

Storage Conditions

This antibody is stable for at least one (1) year at -20°C.

Product Datasheet

https://www.qedbio.com/wp-content/uploads/pdf/56336.pdf

Specificity

Calcineurin A

Formulation

PBS, 50% glycerol, 0.09% sodium azide

Target Background

Calcineurin is a Ca+2/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit and a myristylated regulatory B subunit that binds calcium. It controls the translocation of nuclear factors from the cytosol into the nucleus of activated T cells. Calcineurin is a target of immunosuppressive drugs such as cyclosporin A and FK506.

CAS Number

9007-83-4

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