Robenidine-d8 (hydrochloride)
Robenidine-d8 (hydrochloride) is the deuterium labeled Robenidine hydrochloride. Robenidine hydrochloride is an anticoccidial agent which is also active against MRSA and VRE with MIC50s of 8.1 and 4.7 μM, respectively.
Product Specifications
CAS Number
1173097-77-2
UNSPSC
12352005
Hazard Statement
H302
Target
Bacterial; Parasite
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection
Field of Research
Infection
Purity
99.0
Solubility
10 mM in DMSO|DMSO : 6.25mg/mL (ultrasonic) |H2O : 1mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
N=C(N/N=C/C1=C([2H])C([2H])=C(C([2H])=C1[2H])Cl)N/N=C/C2=C([2H])C([2H])=C(C([2H])=C2[2H])Cl.[H]Cl
Molecular Formula
C15H6D8Cl3N5
Molecular Weight
378.71
Precautions
H302
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Abraham RJ, et al. Robenidine Analogues as Gram-Positive Antibacterial Agents. J Med Chem. 2016 Mar 10;59 (5) :2126-38.|[3]Liu C, et al. Influence of three coccidiostats on the pharmacokinetics of florfenicol in rabbits. Exp Anim. 2015;64 (1) :73-9.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
Coccidia
Available Sizes
Frequently Asked Questions
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