Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz
Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz is a PROTAC linker and a maleimide-GGFG peptide linker. Fmoc-Gly-Gly-Phe-Gly-CH2-O-CH2-Cbz can be used in the synthesis of the Deruxtecan[1].
Product Specifications
CAS Number
[2264011-97-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fmoc-gly-gly-phe-gly-ch2-o-ch2-cbz.html
Purity
99.53
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(OCC1=CC=CC=C1)COCNC(CNC([C@H](CC2=CC=CC=C2)NC(CNC(CNC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O)=O)=O)=O
Molecular Formula
C40H41N5O9
Molecular Weight
735.78
Precautions
H302, H315, H319, H335
References & Citations
[1]NOGUCHI, Shigeru, et al. Method for selectively manufacturing antibody-drug conjugate. WO2017002776A1.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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