KDM2B-IN-4
KDM2B-IN-4 (Compound 182b) is a histone demethylase KDM2B inhibitor with an IC50 of 1.12 nM. KDM2B-IN-4 can be used for the research of hyperproliferative diseases such as cancers[1].
Product Specifications
CAS Number
[1966933-85-6]
UNSPSC
12352005
Target
Histone Demethylase
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/kdm2b-in-4.html
Purity
99.61
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CCC1=C(OC)C=CC2=C1C=CC(C([C@@H]3CN(C4CCC4)CC[C@@H]3C)=O)=C2
Molecular Formula
C24H28N2O2
Molecular Weight
376.49
References & Citations
[1]Albrecht BK, et, al. (piperidin-3-yl) (naphthalen-2-yl) methanone derivatives and related compounds as inhibitors of the histone demethylase kdm2b for the treatment of cancer. WO2016112284A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
KDM2
Available Sizes
Curated Selection
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