KDM2B-IN-4

KDM2B-IN-4 (Compound 182b) is a histone demethylase KDM2B inhibitor with an IC50 of 1.12 nM. KDM2B-IN-4 can be used for the research of hyperproliferative diseases such as cancers[1].

Product Specifications

CAS Number

[1966933-85-6]

UNSPSC

12352005

Target

Histone Demethylase

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/kdm2b-in-4.html

Purity

99.61

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CCC1=C(OC)C=CC2=C1C=CC(C([C@@H]3CN(C4CCC4)CC[C@@H]3C)=O)=C2

Molecular Formula

C24H28N2O2

Molecular Weight

376.49

References & Citations

[1]Albrecht BK, et, al. (piperidin-3-yl) (naphthalen-2-yl) methanone derivatives and related compounds as inhibitors of the histone demethylase kdm2b for the treatment of cancer. WO2016112284A1.